Impact of the dead-time correction method on quantitative 177Lu-SPECT (QSPECT) and dosimetry during radiopharmaceutical therapy

Impact of the dead-time correction method on quantitative 177Lu-SPECT (QSPECT) and dosimetry during radiopharmaceutical therapy

Abstract Background Dead-time correction is required for accurate quantitative SPECT-based dosimetry in the context of personalised 177Lu radiopharmaceutical therapy. We aimed to evaluate the impact of applying dead-time correction on the reconstructed SPECT image versus on the acquisition projectio...

Full description

Bibliographic Details
Main Authors: Alessandro Desy, Guillaume F. Bouvet, Nancy Lafrenière, Atefeh Zamanian, Philippe Després, Jean-Mathieu Beauregard
Format: Article
Language:English
Published: SpringerOpen 2022-08-01
Series:EJNMMI Physics
Subjects:
Quantitative imaging
Single-photon emission computed tomography
Dead time
Dosimetry
Lutetium-177
Radiopharmaceutical therapy
Online Access:https://doi.org/10.1186/s40658-022-00484-w

Internet

https://doi.org/10.1186/s40658-022-00484-w

Similar Items