Genotyping and Molecular Diagnosis of Hepatitis A Virus in Human Clinical Samples Using Multiplex PCR-Based Next-Generation Sequencing

Genotyping and Molecular Diagnosis of Hepatitis A Virus in Human Clinical Samples Using Multiplex PCR-Based Next-Generation Sequencing

Hepatitis A virus (HAV) is a serious threat to public health worldwide. We used multiplex polymerase chain reaction (PCR)-based next-generation sequencing (NGS) to derive information on viral genetic diversity and conduct precise phylogenetic analysis. Four HAV genome sequences were obtained using m...

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Bibliographic Details
Main Authors: Geum-Young Lee, Won-Keun Kim, Seungchan Cho, Kyungmin Park, Jongwoo Kim, Seung-Ho Lee, Jingyeong Lee, Young-Sun Lee, Ji Hoon Kim, Kwan Soo Byun, Jin-Won Song
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
hepatitis A virus
multiplex polymerase chain reaction
next-generation sequencing
phylogenetic analysis
genotypic analysis
Online Access:https://www.mdpi.com/2076-2607/10/1/100

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https://www.mdpi.com/2076-2607/10/1/100

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