Low frequency stimulation for seizure suppression: Identification of optimal targets in the entorhinal-hippocampal circuit

Low frequency stimulation for seizure suppression: Identification of optimal targets in the entorhinal-hippocampal circuit

Background: Mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) is a common form of drug-resistant focal epilepsy in adults. Treatment for pharmacoresistant patients remains a challenge, with deep brain stimulation (DBS) showing promise for alleviating intractable seizures. This stu...

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Bibliographic Details
Main Authors: Piret Kleis, Enya Paschen, Ute Häussler, Carola A. Haas
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Brain Stimulation
Subjects:
Deep brain stimulation
Optogenetics
Kainate
Epilepsy
Perforant path
Dentate granule cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X24000536

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http://www.sciencedirect.com/science/article/pii/S1935861X24000536

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