YMDD motif mutations in chronic hepatitis B antiviral treatment naïve patients: a multi-center study

OBJECTIVE: This study aimed to determine the natural prevalence of variants of tyrosine-methionine-aspartic acid-aspartic acid (YMDD) motif in patients with chronic hepatitis B (CHB), and to explore its relation with demographic and clinical features, hepatitis B virus (HBV) genotypes, and HBV DNA l...

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Bibliographic Details
Main Authors: You-Wen Tan, Guo-Hong Ge, Wei Zhao, Jian-He Gan, Yun Zhao, Zhi-Lin Niu, Dong-Jun Zhang, Li Chen, Xue- Jun Yu, Li-Jun Yang
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300006&lng=en&tlng=en