Histone malonylation is regulated by SIRT5 and KAT2A

Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

Полное описание

Библиографические подробности
Главные авторы:	Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
Формат:	Статья
Язык:	English
Опубликовано:	Elsevier 2023-03-01
Серии:	iScience
Предметы:	Biological sciences Molecular biology Omics Proteomics
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2589004223002705

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