Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

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書目詳細資料
Main Authors: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
格式: Article
語言:English
出版: Elsevier 2023-03-01
叢編:iScience
主題:
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2589004223002705