Rationally engineering santalene synthase to readjust the component ratio of sandalwood oil

Controlling the component ratios of plant essential oils is challenging in their heterologous bioproduction. Here, the authors combine metabolic and enzymatic engineering strategies to achieve the production of sandalwood oil with a desirable component ratio in baker’s yeast.

Bibliographic Details
Main Authors: Wenlong Zha, Fan Zhang, Jiaqi Shao, Xingmei Ma, Jianxun Zhu, Pinghua Sun, Ruibo Wu, Jiachen Zi
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30294-8