Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness

Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness

ABSTRACTInfluenza viruses have an error-prone polymerase complex that facilitates a mutagenic environment. Antigenic mutants swiftly arise from this environment with the capacity to persist in both humans and economically important livestock even in the face of vaccination. Furthermore, influenza vi...

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Bibliographic Details
Main Authors: Joshua E. Sealy, Thomas P. Peacock, Jean-Remy Sadeyen, Pengxiang Chang, Holly J. Everest, Sushant Bhat, Munir Iqbal
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Influenza
antigenic drift
avidity
receptor binding
glycosylation
virus evolution
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1850180

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2020.1850180

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