Interleukin-27 impairs BCG antigen clearance and T cell stimulatory potential by neonatal dendritic cells
Bacille Calmette Guérin (BCG) is a live-attenuated vaccine for protection against Mycobacterium tuberculosis. Despite high disease protection in infancy and early childhood, it generates poor long-term protection against pulmonary tuberculosis. We hypothesized that the unique immune profile that inc...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Current Research in Microbial Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666517422000736 |