The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitis

The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitis

Abstract Background Fra-1 (fosl1) belongs to the activator protein1 (AP-1) family inducing IL-11 expression in oxidative stress condition. IL-11 plays a pivotal role in protecting epithelial barriers integrity. In this study, we investigated the Fra-1 gene expression in the inflamed mucosa of patien...

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Bibliographic Details
Main Authors: Milad Sabzevary-Ghahfarokhi, Mojtaba Shohan, Hedayatollah Shirzad, Ghorbanali Rahimian, Nader Bagheri, Amin Soltani, Fatemeh Deris, Mahdi Ghatreh-Samani, Ehsan Razmara
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Immunology
Subjects:
Oxidative stress
Ulcerative colitis (UC)
Fra-1 gene
IL-11
Online Access:http://link.springer.com/article/10.1186/s12865-018-0257-9

Internet

http://link.springer.com/article/10.1186/s12865-018-0257-9

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