Therapeutic Drug Monitoring of Antifungal Agents in Critically Ill Patients: Is There a Need for Dose Optimisation?

Invasive fungal infections are an important cause of morbidity and mortality, especially in critically ill patients. Increasing resistance rates and inadequate antifungal exposure have been documented in these patients, due to clinically relevant pharmacokinetic (PK) and pharmacodynamic (PD) alterat...

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Bibliographic Details
Main Authors: Daniela Baracaldo-Santamaría, Juan David Cala-Garcia, Germán José Medina-Rincón, Luis Carlos Rojas-Rodriguez, Carlos-Alberto Calderon-Ospina
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/5/645