A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases

A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases

The development of broad-spectrum antivirals against human coronaviruses (HCoVs) is critical to combat the current coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, as well as future outbreaks of emerging CoVs. We ha...

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Bibliographic Details
Main Authors: Jie Zhou, Wei Xu, Zezhong Liu, Chao Wang, Shuai Xia, Qiaoshuai Lan, Yanxing Cai, Shan Su, Jing Pu, Lixiao Xing, Youhua Xie, Lu Lu, Shibo Jiang, Qian Wang
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Coronavirus
Lipopeptide
SARS-CoV-2
Polyethylene glycol
Fusion inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002756

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521002756

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