FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner

FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner

Background Acute kidney injury (AKI) is a frequent complication of severe acute pancreatitis (SAP). Previous investigations have revealed the involvement of FTO alpha-ketoglutarate-dependent dioxygenase (FTO) and aquaporin 3 (AQP3) in AKI. Therefore, the aim of this study is to explore the associati...

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Bibliographic Details
Main Authors: Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Acute kidney injury
fat-mass and obesity-associated protein
aquaporin 3
proximal tubular epithelial cells
N6-methyladenosine modification
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2322037

Internet

https://www.tandfonline.com/doi/10.1080/0886022X.2024.2322037

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