Identification of CNKSR1 as a biomarker for “cold” tumor microenvironment in lung adenocarcinoma: An integrative analysis based on a novel workflow

Identification of CNKSR1 as a biomarker for “cold” tumor microenvironment in lung adenocarcinoma: An integrative analysis based on a novel workflow

Background: Therapies targeting PD1/PD-L1 pathway have revolutionized the treatment of lung cancer. However, anti-PD1/PD-L1 therapies have proven beneficial for only a select group of lung adenocarcinoma (LUAD) patients and generally do not work for immuno-cold tumors characterized by a lack of immu...

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Bibliographic Details
Main Authors: Qidong Cai, Mou Peng
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
CNKSR1
PD-L1
Lung adenocarcinoma
Immunotherapy
Machine learning
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024051570

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024051570

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