Impact of genetic variations on pharmacokinetic and pharmacodynamic properties of medicines and the future of drug therapy
Genetic variations between individuals usually leads to differences in the drug response as it could affect both pharmacokinetic and pharmacodynamic processes. An example of mutation of genes that affect drug targets (pharmacodynamic) is VKORC1 gene that codes for active sites of the enzyme vitamin...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hawler Medical University
2020-06-01
|
| Series: | Zanco Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://zjms.hmu.edu.krd/index.php/zjms/article/view/720/618 |