Case report: Atypical case of autoimmune glial fibrillary acidic protein astrocytopathy following COVID-19 vaccination refractory to immunosuppressive treatments

Case report: Atypical case of autoimmune glial fibrillary acidic protein astrocytopathy following COVID-19 vaccination refractory to immunosuppressive treatments

A 54-year-old Japanese man presented with headache and fever the day after SARS-CoV-2 vaccination. He became deeply unconscious within a week. Brain MRI showed periventricular linear enhancements and a few spotty lesions in the cerebral white matter. Cerebrospinal fluid (CSF) testing showed mild ple...

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Bibliographic Details
Main Authors: Yuto Morishima, Takanori Hata, Sho Nakajima, Kazumasa Shindo, Mai Tsuchiya, Tsubasa Watanabe, Ippei Tahara, Tetsuo Kondo, Akio Kimura, Takayoshi Shimohata, Yuji Ueno
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
GFAP-astrocytopathy
anti-GFAP antibody
COVID-19 vaccination
autoimmune encephalitis
immunosuppressive treatments
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1361685/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1361685/full

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