A Senescence-Like Cellular Response Inhibits Bovine Ephemeral Fever Virus Proliferation

During industrial-scale production of viruses for vaccine manufacturing, anti-viral response of host cells can dampen maximal viral antigen yield. In addition to interferon responses, many other cellular responses, such as the AMPK signaling pathway or senescence-like response may inhibit or slow do...

Full description

Bibliographic Details
Main Authors: Yu-Jing Zeng, Min-Kung Hsu, Chiao-An Tsai, Chun-Yen Chu, Hsing-Chieh Wu, Hsian-Yu Wang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/6/601