Dose Tailoring of Vancomycin Through Population Pharmacokinetic Modeling Among Surgical Patients in Pakistan

Dose Tailoring of Vancomycin Through Population Pharmacokinetic Modeling Among Surgical Patients in Pakistan

Background: Vancomycin is a narrow therapeutic agent, and it is necessary to optimize the dose to achieve safe therapeutic outcomes. The purpose of this study was to identify the significant covariates for vancomycin clearance and to optimize the dose among surgical patients in Pakistan.Methods: Pla...

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Bibliographic Details
Main Authors: Muhammad Muaaz Munir, Huma Rasheed, Muhammad Imran Khokhar, Rizwan Rasul Khan, Hafiz Asad Saeed, Mateen Abbas, Mohsin Ali, Rabiea Bilal, Hafiz Awais Nawaz, Abdul Muqeet Khan, Shaista Qamar, Syed Muneeb Anjum, Muhammad Usman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
vancomycin
population pharmacokinetics
Pakistan
NONMEM
dose tailoring
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.721819/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.721819/full

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