TDO2 deficiency attenuates the hepatic lipid deposition and liver fibrosis in mice with diet-induced non-alcoholic fatty liver disease

TDO2 deficiency attenuates the hepatic lipid deposition and liver fibrosis in mice with diet-induced non-alcoholic fatty liver disease

Purpose: Non-alcoholic fatty liver disease (NAFLD) represents an increasingly prevalent set of liver diseases. Tryptophan 2,3-dioxygenase 2 (TDO2) is the major enzyme of tryptophan catabolism and is abnormally expressed in liver cancer, but the function of TDO2 in NAFLD remains unclear. The current...

Full description

Bibliographic Details
Main Authors: Zhi Qin, Min Zhou
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
TDO2
NF-κB
Hepatic lipid deposition
Liver fibrosis
NAFLD
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402309672X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402309672X

Similar Items