Deciphering the heterogeneity of the Lyve1+ perivascular macrophages in the mouse brain

Perivascular macrophages (pvMs) are important for brain drainage and immune regulation. Here the authors analyse various reporter mouse strains for finer mapping of pvM subsets and lineage differentiation, and propose CX3CR1negative and CD45low as additional markers of intermediate pvMs for studying...

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Bibliographic Details
Main Authors: C. Siret, M. van Lessen, J. Bavais, H. W. Jeong, S. K. Reddy Samawar, K. Kapupara, S. Wang, M. Simic, L. de Fabritus, A. Tchoghandjian, M. Fallet, H. Huang, S. Sarrazin, M. H. Sieweke, R. Stumm, L. Sorokin, R. H. Adams, S. Schulte-Merker, F. Kiefer, S. A. van de Pavert
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35166-9