Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis
Protease-activated receptor-2 (PAR2), primarily involved in inflammation, is highly expressed in limbic regions of the brain such as the hippocampus. Although extracellular proteolysis is involved in normal and stress-related neuronal plasticity associated with learning, memory and inflammatory dise...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-04-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996107002732 |