Glycosylation of Trypanosoma cruzi TcI antigen reveals recognition by chagasic sera

Abstract Chagas disease is considered the most important parasitic disease in Latin America. The protozoan agent, Trypanosoma cruzi, comprises six genetic lineages, TcI-TcVI. Genotyping to link lineage(s) to severity of cardiomyopathy and gastrointestinal pathology is impeded by the sequestration an...

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Bibliographic Details
Main Authors: Niamh Murphy, Barrie Rooney, Tapan Bhattacharyya, Omar Triana-Chavez, Anja Krueger, Stuart M. Haslam, Victoria O’Rourke, Magdalena Pańczuk, Jemima Tsang, Jack Bickford-Smith, Robert H. Gilman, Kevin Tetteh, Chris Drakeley, C. Mark Smales, Michael A. Miles
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-73390-9