Rational Design 2-Hydroxypropylphosphonium Salts as Cancer Cell Mitochondria-Targeted Vectors: Synthesis, Structure, and Biological Properties

Rational Design 2-Hydroxypropylphosphonium Salts as Cancer Cell Mitochondria-Targeted Vectors: Synthesis, Structure, and Biological Properties

It has been shown for a wide range of epoxy compounds that their interaction with triphenylphosphonium triflate occurs with a high chemoselectivity and leads to the formation of (2-hydroxypropyl)triphenylphosphonium triflates <b>3</b> substituted in the 3-position with an alkoxy, alkylca...

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Bibliographic Details
Main Authors: Vladimir F. Mironov, Andrey V. Nemtarev, Olga V. Tsepaeva, Mudaris N. Dimukhametov, Igor A. Litvinov, Alexandra D. Voloshina, Tatiana N. Pashirova, Eugenii A. Titov, Anna P. Lyubina, Syumbelya K. Amerhanova, Aidar T. Gubaidullin, Daut R. Islamov
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
phosphonium salt
P–C bond formation
oxirane
glycidyl ether
triphenylphosphine
addition reaction
Online Access:https://www.mdpi.com/1420-3049/26/21/6350

Internet

https://www.mdpi.com/1420-3049/26/21/6350

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