Superoxide increases angiotensin II AT1 receptor function in human kidney‐2 cells

The redox‐sensitive Sp family transcription factor has been linked to the regulation of angiotensin II type 1 receptor (AT1R). However, the exact mechanism of AT1R regulation in renal cells is poorly understood. We tested the specificity of reactive oxygen species (ROS), superoxide vs. hydrogen pero...

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Bibliographic Details
Main Authors: Mohammad Saleem, Indira Pokkunuri, Mohammad Asghar
Format: Article
Language:English
Published: Wiley 2016-12-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12148