Excipient Interactions in Glucagon Dry Powder Inhaler Formulation for Pulmonary Delivery

Excipient Interactions in Glucagon Dry Powder Inhaler Formulation for Pulmonary Delivery

Purpose: This study describes the development and characterization of glucagon dry powder inhaler (DPI) formulation for pulmonary delivery. Lactose monohydrate, as a carrier, and L-leucine and magnesium stearate (MgSt) were used as dispersibility enhancers for this formulation. Methods: Using Fourie...

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Bibliographic Details
Main Authors: Md Abdur Rashid, Amged Awad Elgied, Yahya Alhamhoom, Enoch Chan, Llew Rintoul, Ayman Allahham, Nazrul Islam
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Pharmaceutics
Subjects:
glucagon
dry powder inhaler formulation
pulmonary drug delivery
excipients interactions
fine particle fractions
FTIR
DSC
Online Access:https://www.mdpi.com/1999-4923/11/5/207

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https://www.mdpi.com/1999-4923/11/5/207

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