Horizontal Gene Transfer of Triazole Resistance in Aspergillus fumigatus

Horizontal Gene Transfer of Triazole Resistance in Aspergillus fumigatus

ABSTRACT Aspergillus fumigatus is the primary mold pathogen in humans. It can cause a wide range of diseases in humans, with high mortality rates in immunocompromised patients. The first-line treatments for invasive A. fumigatus infections are the triazole antifungals that inhibit Cyp51 lanosterol d...

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Bibliographic Details
Main Authors: Alma Morogovsky, Mariana Handelman, Ammar Abou Kandil, Yona Shadkchan, Nir Osherov
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
Aspergillus fumigatus
horizontal gene transfer
triazole antifungals
drug resistance
hyphal fusion
antifungal resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01112-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01112-22

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