Genome-Wide Investigation of Pasteurella multocida Identifies the Stringent Response as a Negative Regulator of Hyaluronic Acid Capsule Production

Genome-Wide Investigation of Pasteurella multocida Identifies the Stringent Response as a Negative Regulator of Hyaluronic Acid Capsule Production

ABSTRACT Pasteurella multocida is a Gram-negative capsulated bacterium responsible for a range of diseases that cause severe morbidity and mortality in livestock animals. The hyaluronic acid (HA) capsule produced by P. multocida serogroup A strains is a critical virulence factor. In this study, we u...

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Bibliographic Details
Main Authors: Thomas R. Smallman, Galain C. Williams, Marina Harper, John D. Boyce
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
Pasteurella multocida
capsule
hyaluronic acid
stringent response
P. multocida
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00195-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00195-22

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