Longitudinal markers of cerebral amyloid angiopathy and related inflammation in rTg-DI rats

Longitudinal markers of cerebral amyloid angiopathy and related inflammation in rTg-DI rats

Abstract Cerebral amyloid angiopathy (CAA) is a prevalent vascular dementia and common comorbidity of Alzheimer’s disease (AD). While it is known that vascular fibrillar amyloid β (Aβ) deposits leads to vascular deterioration and can drive parenchymal CAA related inflammation (CAA-ri), underlying me...

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Bibliographic Details
Main Authors: Joseph M. Schrader, Feng Xu, Kevin J. Agostinucci, Nicholas A. DaSilva, William E. Van Nostrand
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Cerebral amyloid angiopathy
Transgenic rats
Neuroinflammation
Proteomics
Biomarkers
Online Access:https://doi.org/10.1038/s41598-024-59013-7

Internet

https://doi.org/10.1038/s41598-024-59013-7

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