Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from <i>Isolona hexaloba</i> on Rhodamine Efflux by Abcb1b from Rat Glycocholic-Acid-Resistant Hepatocarcinoma Cells

To develop new therapeutic molecules, it is essential to understand the biological effects and targets of clinically relevant compounds. In this article, we describe the extraction and characterization of two alkaloids from the roots of <i>Isolona hexaloba</i>—curine and guattegaumerine....

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Bibliographic Details
Main Authors: Jacques-Aurélien Sergent, Hilarion Mathouet, Christian Hulen, Pedro Lameiras, Marc Feuilloley, Abdelhakim Elomri, Nour-Eddine Lomri
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/9/3030