Towards a unified model of naive T cell dynamics across the lifespan

Naive CD4 and CD8 T cells are cornerstones of adaptive immunity, but the dynamics of their establishment early in life and how their kinetics change as they mature following release from the thymus are poorly understood. Further, due to the diverse signals implicated in naive T cell survival, it has...

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Bibliographic Details
Main Authors: Sanket Rane, Thea Hogan, Edward Lee, Benedict Seddon, Andrew J Yates
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/78168