A novel amino acid signaling process governs glucose-6-phosphatase transcription

A novel amino acid signaling process governs glucose-6-phosphatase transcription

Summary: Emerging evidence has shown that amino acids act as metabolic regulatory signals. Here, we showed that glucose-6-phosphatase (G6Pase) mRNA levels in cultured hepatocyte models were downregulated in an amino-acid-depleted medium. Inversely, stimulation with amino acids increased G6Pase mRNA...

Full description

Bibliographic Details
Main Authors: Sara Fukushima, Hiroki Nishi, Mikako Kumano, Daisuke Yamanaka, Naoyuki Kataoka, Fumihiko Hakuno, Shin-Ichiro Takahashi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
Natural Sciences
Biological Sciences
Biochemistry
Molecular Biology
Molecular Mechanism of Gene Regulation
Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100746X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422100746X

Similar Items