Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells.

Chronic exposure to polychlorinated biphenyls (PCBs), ubiquitous environmental contaminants, can adversely affect the development and function of the nervous system. Here we evaluated the effect of PCB exposure on mitochondrial function using the PCB mixture Aroclor-1254 (A1254) in SH-SY5Y neuroblas...

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Main Authors: Stefania Cocco, Agnese Secondo, Adelaide Del Viscovo, Claudio Procaccini, Luigi Formisano, Cristina Franco, Alba Esposito, Antonella Scorziello, Giuseppe Matarese, Gianfranco Di Renzo, Lorella Maria Teresa Canzoniero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4477897?pdf=render