Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

<p>Abstract</p> <p>Background</p> <p>CCR5-restricted (R5) human immunodeficiency virus type 1 (HIV-1) variants cause CD4+ T-cell loss in the majority of individuals who progress to AIDS, but mechanisms underlying the pathogenicity of R5 strains are poorly understood. To...

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Bibliographic Details
Main Authors: Wang Bin, Saksena Nitin, Purcell Damian FJ, Dunfee Rebecca L, Roche Michael J, Gray Lachlan R, Ellett Anne, Churchill Melissa J, Sterjovski Jasminka, Sonza Secondo, Wesselingh Steven L, Karlsson Ingrid, Fenyo Eva-Maria, Gabuzda Dana, Cunningham Anthony L, Gorry Paul R
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/89

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http://www.retrovirology.com/content/4/1/89

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