Evidence for widespread existence of functional novel and non-canonical human transcripts

Evidence for widespread existence of functional novel and non-canonical human transcripts

Abstract Background Fraction of functional sequence in the human genome remains a key unresolved question in Biology and the subject of vigorous debate. While a plethora of studies have connected a significant fraction of human DNA to various biochemical processes, the classical definition of functi...

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Bibliographic Details
Main Authors: Dongyang Xu, Lu Tang, Junjun Zhou, Fang Wang, Huifen Cao, Yu Huang, Philipp Kapranov
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Biology
Subjects:
Insertional mutagenesis
Functional genomics
RNA dark matter
Non-canonical transcript
Novel exon
Alternative splicing
Online Access:https://doi.org/10.1186/s12915-023-01753-5

Internet

https://doi.org/10.1186/s12915-023-01753-5

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