Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line

Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line

SARS-CoV-2, which emerged in Wuhan (China), has become a great worldwide problem in 2020 and has led to more than 1,000,000 deaths worldwide. Many laboratories are searching for ways to fight this pandemic. We studied the action of the cellular antiviral protein tetherin, which is encoded by the BST...

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Bibliographic Details
Main Authors: Alexander A. Dolskiy, Sergei A. Bodnev, Anastasia A. Nazarenko, Anastasia M. Smirnova, Olga G. Pyankova, Anna K. Matveeva, Irina V. Grishchenko, Tatiana V. Tregubchak, Oleg V. Pyankov, Alexander B. Ryzhikov, Elena V. Gavrilova, Rinat A. Maksyutov, Dmitry V. Yudkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
SARS-CoV
SARS-CoV-2
influenza
BST2
tetherin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.616798/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.616798/full

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