Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine

Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine

Chemotherapy-induced cachexia causes severe metabolic abnormalities independently of cancer and reduces the therapeutic efficacy of chemotherapy. The underlying mechanism of chemotherapy-induced cachexia remains unclear. Here we investigated the cytarabine (CYT)-induced alteration in energy balance...

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Bibliographic Details
Main Authors: Mi-Rae Park, Hye-Jin Lee, Hye-Min Jang, Nam Hoon Kim, Jun-Seok Lee, Yong Taek Jeong, Inho Kim, Sang-Hyun Choi, Kwan Sik Seo, Dong-Hoon Kim
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Lipid Research
Subjects:
cytarabine
triglycerides
metabolic dysfunction
cachexia
malabsorption
small intestine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000603

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http://www.sciencedirect.com/science/article/pii/S0022227523000603

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