miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion.
Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial. Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer. Surprisingly, miR-100 inhibits t...
| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Public Library of Science (PLoS)
2014-02-01
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| シリーズ: | PLoS Genetics |
| オンライン･アクセス: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004177&type=printable |