Pharmacogenomic of LH and its receptor: are we ready for clinical practice?

Abstract Luteinizing hormone (LH) is fundamental to support development and reproduction. It acts through a receptor expressed in the gonads, modulating mitogenic, anti-apoptotic, and steroidogenic signals. LH is also marketed as a drug for controlled ovarian stimulation (COS), where it is administe...

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Bibliographic Details
Main Authors: Alessandro Conforti, Raffaella Di Girolamo, Maurizio Guida, Carlo Alviggi, Livio Casarini
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-025-01359-2