A novel HIV vaccine targeting the protease cleavage sites

A novel HIV vaccine targeting the protease cleavage sites

Abstract HIV preferentially infects activated CD4+ T cells and mutates rapidly. The classical vaccine approach aimed to generate broad immune responses to full HIV proteins largely failed to address the potential adverse impact of increased number of activated CD4+ T cells as viral targets. Learning...

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Bibliographic Details
Main Authors: Hongzhao Li, Robert W. Omange, Francis A. Plummer, Ma Luo
Format: Article
Language:English
Published: BMC 2017-09-01
Series:AIDS Research and Therapy
Subjects:
HIV
Vaccine
Protease cleavage sites
Natural immunity
Pumwani sex worker cohort
Nonhuman primate
Online Access:http://link.springer.com/article/10.1186/s12981-017-0174-7

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http://link.springer.com/article/10.1186/s12981-017-0174-7

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