Repurposing hydrochlorothiazide (HCTZ) for colorectal cancer: a retrospective and single center study

Repurposing hydrochlorothiazide (HCTZ) for colorectal cancer: a retrospective and single center study

BackgroundAnti-hypertensive drugs have been reported to demonstrate anti-inflammatory and anti-angiogenic effects. This study aims to investigate the association between anti-hypertensive drugs and the prognosis of colorectal cancer (CRC) patients.MethodsClinical data of 1134 CRC patients with hyper...

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Bibliographic Details
Main Authors: Dominic Chi-Chung Foo, Jiaxi Li, Zheng Huang, Siming Sui, Ryan Wai-Yan Sin, Abraham Tak Ka Man, Wai-Lun Law, Lui Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
colorectal cancer
drug repurposing
antihypertensive drugs
hydrochlorothiazide
basophil
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1449062/full

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https://www.frontiersin.org/articles/10.3389/fphar.2025.1449062/full

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