A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol

Abstract Background Neuropathic pain affects 7–10% of people, but responds poorly to pharmacotherapy, indicating a need for better treatments. Mechanistic research on neuropathic pain frequently uses human surrogate models of the secondary hyperalgesia that is a common feature of neuropathic pain. E...

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Bibliographic Details
Main Authors: Victoria J. Madden, Gillian J. Bedwell, Prince C. Chikezie, Andrew S. C. Rice, Peter R. Kamerman
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Systematic Reviews
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13643-019-1120-7