Acid Sphingomyelinase Controls Early Phases of Skeletal Muscle Regeneration by Shaping the Macrophage Phenotype

Acid Sphingomyelinase Controls Early Phases of Skeletal Muscle Regeneration by Shaping the Macrophage Phenotype

Skeletal muscle regeneration is a complex process involving crosstalk between immune cells and myogenic precursor cells, i.e., satellite cells. In this scenario, macrophage recruitment in damaged muscles is a mandatory step for tissue repair since pro-inflammatory M1 macrophages promote the activati...

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Bibliographic Details
Main Authors: Paulina Roux-Biejat, Marco Coazzoli, Pasquale Marrazzo, Silvia Zecchini, Ilaria Di Renzo, Cecilia Prata, Alessandra Napoli, Claudia Moscheni, Matteo Giovarelli, Maria Cristina Barbalace, Elisabetta Catalani, Maria Teresa Bassi, Clara De Palma, Davide Cervia, Marco Malaguti, Silvana Hrelia, Emilio Clementi, Cristiana Perrotta
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
acid sphingomyelinase
muscle regeneration
macrophage phenotype
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/11/3028

Internet

https://www.mdpi.com/2073-4409/10/11/3028

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