The discovery of potential tumor necrosis factor alpha converting enzyme inhibitors via implementation of K Nearest Neighbor QSAR analysis

Tumor necrosis factor-alpha converting enzyme (TACE) is considered as a pro-inflammatory cytokine which catalyzes the formation of TNF-α from membrane bound TNF-α precursor protein. It has important role in various pathological diseases such as inflammation, anorexia, rheumatoid arthritis, cancer an...

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Bibliographic Details
Main Authors: Maha Habash, Sami Alshakhshir, Shady Awwad, Mahmoud Abu-Samak
Format: Article
Language:English
Published: Pensoft Publishers 2023-04-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/96423/download/pdf/