Space-efficient computation of k-mer dictionaries for large values of k

Abstract Computing k-mer frequencies in a collection of reads is a common procedure in many genomic applications. Several state-of-the-art k-mer counters rely on hash tables to carry out this task but they are often optimised for small k as a hash table keeping keys explicitly (i.e., k-mer sequences...

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Bibliographic Details
Main Authors: Diego Díaz-Domínguez, Miika Leinonen, Leena Salmela
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:https://doi.org/10.1186/s13015-024-00259-1