Transcriptome diversity is a systematic source of variation in RNA-sequencing data.

RNA sequencing has been widely used as an essential tool to probe gene expression. While standard practices have been established to analyze RNA-seq data, it is still challenging to interpret and remove artifactual signals. Several biological and technical factors such as sex, age, batches, and sequ...

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Bibliographic Details
Main Authors: Pablo E García-Nieto, Ban Wang, Hunter B Fraser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009939