Long Non-Coding RNA MALAT1 Protects Human Osteoblasts from Dexamethasone-Induced Injury via Activation of PPM1E-AMPK Signaling

Long Non-Coding RNA MALAT1 Protects Human Osteoblasts from Dexamethasone-Induced Injury via Activation of PPM1E-AMPK Signaling

Background/Aims: Dexamethasone (Dex) induces injuries to human osteoblasts. In this study, we tested the potential role of the long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (Lnc-MALAT1) in this process. Materials: Two established human osteoblastic cell lines (OB-6 and h...

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Bibliographic Details
Main Authors: Jian-bo Fan, Yingzi Zhang, Wei Liu, Xin-hui Zhu, Da-wei Xu, Jian-ning Zhao, Zhi-ming  Cui
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
LncRNA MALAT1
Osteoblasts
Dexamethasone
Nrf2
Online Access:https://www.karger.com/Article/FullText/495159

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https://www.karger.com/Article/FullText/495159

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