Single‐Cell Spatial Transcriptomics Unveils Platelet‐Fueled Cycling Macrophages for Kidney Fibrosis

Single‐Cell Spatial Transcriptomics Unveils Platelet‐Fueled Cycling Macrophages for Kidney Fibrosis

Abstract With the increasing incidence of kidney diseases, there is an urgent need to develop therapeutic strategies to combat post‐injury fibrosis. Immune cells, including platelets, play a pivotal role in this repair process, primarily through their released cytokines. However, the specific role o...

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Bibliographic Details
Main Authors: Jun Liu, Bo Zheng, Qingya Cui, Yu Zhu, Likai Chu, Zhi Geng, Yiming Mao, Lin Wan, Xu Cao, Qianwei Xiong, Fujia Guo, David C Yang, Ssu‐Wei Hsu, Ching‐Hsien Chen, Xiangming Yan
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Advanced Science
Subjects:
kidney fibrosis
macrophage proliferation
platelet
thrombospondin 1
Online Access:https://doi.org/10.1002/advs.202308505

Internet

https://doi.org/10.1002/advs.202308505

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