Matrix Effects in GC–MS Profiling of Common Metabolites after Trimethylsilyl Derivatization

Matrix Effects in GC–MS Profiling of Common Metabolites after Trimethylsilyl Derivatization

Metabolite profiling using gas chromatography coupled to mass spectrometry (GC–MS) is one of the most frequently applied and standardized methods in research projects using metabolomics to analyze complex samples. However, more than 20 years after the introduction of non-targeted approaches using GC...

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Bibliographic Details
Main Authors: Elena Tarakhovskaya, Andrea Marcillo, Caroline Davis, Sanja Milkovska-Stamenova, Antje Hutschenreuther, Claudia Birkemeyer
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
quantification
gas chromatography–mass spectrometry
metabolomics
signal suppression
signal enhancement
compound saturation
Online Access:https://www.mdpi.com/1420-3049/28/6/2653

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https://www.mdpi.com/1420-3049/28/6/2653

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