Validation of elevated levels of interleukin-8 in the cerebrospinal fluid, and discovery of new biomarkers in patients with GBS and CIDP using a proximity extension assay

Validation of elevated levels of interleukin-8 in the cerebrospinal fluid, and discovery of new biomarkers in patients with GBS and CIDP using a proximity extension assay

BackgroundBiomarkers for diagnosis of inflammatory neuropathies, assessment of prognosis, and treatment response are lacking.MethodsCSF and EDTA plasma from patients with Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), healthy controls (HC) and disease contro...

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Bibliographic Details
Main Authors: Ivan Kmezic, Rasmus Gustafsson, Katharina Fink, Anders Svenningsson, Kristin Samuelsson, Caroline Ingre, Tomas Olsson, Magnus Hansson, Ingrid Kockum, Milena Z. Adzemovic, Rayomand Press
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Guillain-Barré syndrome
chronic inflammatory demyelinating polyneuropathy
paraproteinemia-related demyelinating polyneuropathy
multifocal motor neuropathy
interleukin-8
cerebrospinal fluid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1241199/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1241199/full

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