TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Human respiratory syncytial virus (RSV) constitute highly pathogenic virus that cause severe respiratory diseases in newborn, children, elderly and immuno-compromised individuals. Airway inflammation is a critical regulator of disease outcome in RSV infected hosts. Although "controlled" in...

Full description

Bibliographic Details
Main Authors: Jesus Segovia, Ahmed Sabbah, Victoria Mgbemena, Su-Yu Tsai, Te-Hung Chang, Michael T Berton, Ian R Morris, Irving C Allen, Jenny P-Y Ting, Santanu Bose
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266238?pdf=render

Internet

http://europepmc.org/articles/PMC3266238?pdf=render

Similar Items